It also gives them hope that long-term sobriety is possible. It gave me courage to speak because I was always afraid to speak in meetings. But it also gave me courage because I was telling the room that, finally, I did something right. Getting applause for staying sober helped my self-esteem because before I got […]
Nighttime is often reserved for free time when you can call loved ones, read books, or watch television. Movie dates are a classic choice, but they’re especially fun while sober. Choosing a feature that’s more involved or complex sans alcohol means you can follow all the twists and turns. You don’t have to worry about having […]
Having more than three drinks in one sitting temporarily raises blood pressure. Repeated binge drinking can lead to long-term increases in blood pressure. But if you’re younger than 50, particularly if you’re a woman, it’s not so clear. Studies have shown a rise in breast cancer risk in women under 50 from drinking alcohol. While […]
This sort of compulsive use can lead to tolerance and dependence, the hallmarks of addiction. Maybe the advent of nitazenes will finally persuade policymakers to stop digging. Drug prohibition drives the creation of more potent drug forms to enhance business efficiency. Smaller drug packages simplify smuggling, enabling dealers to subdivide stronger forms into smaller portions […]
Abuse of tobacco, alcohol, illicit drugs and prescription opioids costs the United States more than $740 billion each year in crime, health care and lost productivity, according to the National Institute on Drug Abuse. Recovery is a journey, and that means there will be bumps along the way. Everyone struggles during their journey, and being […]
You’ll be able to provide support in a healthy and constructive way. When planning to stage an intervention, it’s essential to speak with a professional first. Intervention specialists are trained to successfully guide families through the process. They will also provide advice on how to seek help for the individual you are trying to get […]
After completing treatment for AUD, it’s possible to have a risk of relapse. It’s important to recognize warning signs and seek help if you’re concerned about having a relapse. Another complication is alcohol withdrawal syndrome, which may occur after you stop drinking and can cause symptoms such as nausea, shaking, and sweating. It can also […]
A heavy alcoholic drink like whiskey, brandy, or rum can dehydrate you more than lighter drinks. Stick to beer and wine to mitigate any dehydration you may experience. A vodka water or vodka soda is probably your best bet if hydration is a goal while drinking. This choice is great because you’re drinking water at […]
This figure shows drugs that can inhibit the VEGF pathway and hence decrease the production of NO and prostacyclin (PGI2). Alflibercept and bevacizumab bind directly to vascular endothelial growth factor A (VEGF A), while small drugs such as sunitinib block the tyrosine kinase domain (TK) of the vascular endothelial growth factor receptor 2 (VEGFR2). There […]
Fentanyl has been shown to exert its analgesic and lethal effects through different receptor populations in the CNS. It is eliminated from cerebrospinal fluid at approximately the same rate as morphine70,71. Acute naloxone administration antagonizes fentanyl-induced analgesia more than fentanyl-induced lethality. Β-funaltrexamine was shown to inhibit both fentanyl-induced analgesia and lethality71. Overdose-related concentrations of fentanyl […]